Andrew S. Cotton

Childhood Maltreatment and Deviations from Normative Brain Structure: Results from 3,711 Individuals from the ENIGMA MDD and ENIGMA PTSD

The paper examines how childhood maltreatment affects brain structure in 3,711 individuals with MDD and PTSD, finding age- and sex-specific brain morphometric differences.

Volumetric Differences of Thalamic Nuclei are Associated with Post-Trauma Psychopathology

The paper examines thalamic volume differences in trauma-exposed individuals with PTSD, MDD, and controls, finding specific volume reductions and associations with symptom severity and childhood trauma.

Multimodal Imaging-Based Classification of PTSD Using Data-Driven Computational Approaches: A Multisite Big Data Study from the ENIGMA-PGC PTSD Consortium

This paper classifies PTSD vs. controls using MRI data from multiple sites, finding better performance when distinguishing PTSD from trauma-unexposed controls than trauma-exposed controls, and showing DVAE improves generalizability.

Smaller total and subregional cerebellar volumes in posttraumatic stress disorder: a mega-analysis by the ENIGMA-PGC PTSD workgroup

This study finds smaller total and subregional cerebellar volumes in PTSD compared to controls using a large dataset and advanced parcellation methods.

A Comparison of Methods to Harmonize Cortical Thickness Measurements Across Scanners and Sites

This paper compares four methods for harmonizing cortical thickness data across multiple sites and finds that ComBat-GAM is most effective in detecting case-control differences and age-related cortical thinning.

Structural Covariance Networks in Post-Traumatic Stress Disorder: A Multisite ENIGMA-PGC Study

This study examines structural covariance networks in PTSD using a large multisite dataset, finding differences in centrality measures between PTSD and control groups, and highlighting sex-based and comorbid differences.