Lauren E. Salminen

Image-Based Meta- and Mega-Analysis (IBMMA): A Unified Framework for Large-Scale, Multi-Site, Neuroimaging Data Analysis

IBMMA improves neuroimaging analysis by handling missing data and large datasets, revealing new brain region findings overlooked by traditional methods.

Multimodal Imaging-Based Classification of PTSD Using Data-Driven Computational Approaches: A Multisite Big Data Study from the ENIGMA-PGC PTSD Consortium

This paper classifies PTSD vs. controls using MRI data from multiple sites, finding better performance when distinguishing PTSD from trauma-unexposed controls than trauma-exposed controls, and showing DVAE improves generalizability.

Smaller total and subregional cerebellar volumes in posttraumatic stress disorder: a mega-analysis by the ENIGMA-PGC PTSD workgroup

This study finds smaller total and subregional cerebellar volumes in PTSD compared to controls using a large dataset and advanced parcellation methods.

A Comparison of Methods to Harmonize Cortical Thickness Measurements Across Scanners and Sites

This paper compares four methods for harmonizing cortical thickness data across multiple sites and finds that ComBat-GAM is most effective in detecting case-control differences and age-related cortical thinning.

Hippocampal subfield volumes are uniquely affected in PTSD and depression: International analysis of 31 cohorts from the PGC-ENIGMA PTSD Working Group

This study identifies hippocampal subfield volume differences in PTSD and depression across 31 cohorts, finding depression has a stronger effect than PTSD, especially in CA1, with comorbid cases showing more pronounced changes.

Altered White Matter Microstructural Organization in Post-Traumatic Stress Disorder across 3,049 Adults: Results from the PGC-ENIGMA PTSD Consortium

This study identifies reduced fractional anisotropy in the tapetum region of the corpus callosum in PTSD patients using a large multi-cohort analysis of diffusion MRI data.

Altered cortical brain structure and increased risk for disease seen decades after perinatal exposure to maternal smoking: A study of 9,000 adults in the UK Biobank

This study finds that perinatal exposure to maternal smoking is associated with reduced cortical surface area in specific brain regions and increased disease risk in middle-aged and older adults.

Adaptive Identification of Cortical and Subcortical Imaging Markers of Early Life Stress and Posttraumatic Stress Disorder

This study uses a machine learning method to identify neuroimaging markers of PTSD and ELS in veterans, finding that combinatorial features improve classification accuracy.