Engineering a soft tumor microenvironment: fibrin-enriched hydrogel promotes cancer cell invasion in a 3D bioprinted colorectal cancer model
Melika Parchehbaf Kashani, Jordi Comelles, Pol Barcelona, Núria Torras, Lorena Diéguez, María García-Díaz, Elena Martinez
This study develops a 3D bioprinted colorectal cancer model using fibrin-enriched hydrogels to show that softer matrices promote cancer cell invasion and stromal interactions.
bioRxiv · Jan 8, 2026 · PreprintBioengineering