Jordi Comelles

Engineering a soft tumor microenvironment: fibrin-enriched hydrogel promotes cancer cell invasion in a 3D bioprinted colorectal cancer model

This study develops a 3D bioprinted colorectal cancer model using fibrin-enriched hydrogels to show that softer matrices promote cancer cell invasion and stromal interactions.

3D micropatterned traction force microscopy: a technique to control three-dimensional cell shape while measuring cell-substrate force transmission.

This paper introduces 3D-TFM to measure cell-substrate forces in 3D environments and shows cells switch from contractile to extensile behavior as volume decreases.