Brian C. Thomas

This paper develops compact adenine base editors for in vivo gene editing, demonstrating their application in Duchenne muscular dystrophy by enabling exon skipping through targeted splice-site disruption.

The paper links genomically novel soil microbes to depth-stratified carbon and nitrogen cycling by analyzing metagenomic and proteomic data from grassland soils.

The paper introduces EukRep, a method to recover eukaryotic genomes from metagenomic samples, demonstrating its utility in analyzing microbial community responses to environmental changes.