Payal Vaswani

Alpha-tocopherol conjugated DNA tetrahedron with enhanced cellular uptake and selective cytotoxicity for cancer therapeutics

This paper develops a DNA tetrahedron conjugated with alpha-tocopherol to enhance cellular uptake and selectively kill cancer cells through ROS-induced apoptosis.

Neurotransmitter loaded DNA nanocages as potential therapeutics for α-synuclein based neuropathies in cells and in vivo

This study investigates DNA nanocages loaded with neurotransmitters as a therapeutic approach to clear α-synuclein aggregates in Parkinson's disease models in cells and zebrafish.

Competence of DNA Tetrahedron and Exosomes as Nanocarriers for Epirubicin drug delivery in Breast Cancer Cells

This study compares DNA tetrahedron and exosome-based delivery of epirubicin in breast cancer cells, finding that DNA tetrahedrons enhance drug delivery and apoptosis more effectively than exosomes or free drug.

Designer DNA nanocages modulate anti-oxidative and anti-inflammatory responses in tumor associated macrophages

This study investigates the immunomodulatory effects of DNA tetrahedrons on tumor-associated macrophages, showing their ability to modulate anti-oxidative and anti-inflammatory responses via PD-L1 regulation.