Author

Caitlin J. Risener

Emory UniversityORCID 0000-0002-4824-6064Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:structural biology· 1

Frequent Co-Authors

Alexa A. SnyderiD· 1 shared Isabella L. KaufmaniD· 1 shared Karen A. KirbyiD· 1 shared Stefan G. SarafianosiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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1 shared paperBiochemistry

Alexa A. SnyderORCID

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1 paper

Recent·Most cited

BiochemistrybioRxivPreprintApr 7, 2026

HIV-1 Reverse Transcriptase interactions with Long-acting NNRTI, Depulfavirine (VM1500A)

Alexa A. Snyder, Isabella L. Kaufman, Caitlin J. Risener…·Stefan G. Sarafianos

This study reports the crystal structure of HIV-1 reverse transcriptase bound to depulfavirine, showing its extended binding conformation and resistance to common mutations, along with combination efficacy with other antivirals.

2 citations

humanstructural biology

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