Author

Yanwu Yang

Indiana University IndianapolisORCID 0000-0002-4832-2987Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:rat· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Michael Aaron WeissiD· 2 shared Yen‐Shan CheniD· 2 shared Alan D. CherringtoniD· 1 shared Alicia BelgoroskyiD· 1 shared Carmen Malosetti· 1 shared Chun‐Lun NiiD· 1 shared Deepak ChatterjeeiD· 1 shared Elisa VaianiiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersBioengineering

Michael Aaron WeissORCID

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2 papers

Recent·Most cited

Ultra-stable insulin-glucagon fusion protein exploits an endogenous hepatic switch to mitigate hypoglycemic risk

Nicolás Varas, Mark A. Jarosinski, Yen‐Shan Chen, Chun‐Lun Ni, Rachel Grabowski, Ningwen Tai, Raimund I. Herzog, Faramarz Ismail‐Beigi, Yanwu Yang, Alan D. Cherrington, Michael Aaron Weiss

This paper develops an ultra-stable insulin-glucagon fusion protein that exploits a hepatic glucose switch to reduce hypoglycemic risk in diabetes, showing improved stability and glycemic control in rats.

ACS Pharmacology & Translational Science · Aug 14, 2025Peer-reviewedBioengineering

Genetic, Genomic and Biophysical Case Study: Familial 46, XY Sex Reversal due to a Novel Inherited Mutation in Human Testis-Determining Factor SRY

Elisa Vaiani, Yen‐Shan Chen, Pablo Ramírez, Joseph D. Racca, María Sonia Baquedano, Carmen Malosetti, María Sol Touzón, Roxana Marcela Marino, Mariana Costanzo, Marcela Bailez, Esperanza Beatriz Berensztein, Maria Laura Galluzzo-Mutti, Deepak Chatterjee, Yanwu Yang, Alicia Belgorosky, Michael Aaron Weiss

The paper describes a novel SRY mutation causing 46, XY sex reversal, showing its partial function and phenotypic effects in a family.

bioRxiv · May 5, 2021 · PreprintDevelopmental Biology