Rosa A. Serra

SRY-Box Transcription Factor 9 regulates 3'-Phosphoadenosine 5'-Phosphosulfate Synthase 2 mRNA expression through derepression of the transcriptional repressor, CCAAT/enhancer-binding protein beta

This paper identifies a Sox9-dependent regulatory mechanism for Papss2 expression, showing Sox9 derepresses C/EBPβ to enhance transcription.

TGFβ signaling is required for sclerotome resegmentation during development of the spinal column in Gallus gallus.

This study shows that TGFβ signaling is required for sclerotome resegmentation in chick embryos, leading to vertebral malformations and disrupted rostro-caudal patterning.

Canonical and noncanonical TGF-β signaling regulate fibrous tissue differentiation in the axial skeleton

This study shows TGF-β regulates fibrous tissue markers in sclerotome via both canonical Smad3 and noncanonical ERK1/2 pathways, with Scleraxis acting as an intermediate.

Tgfbr2 in dental pulp cells guides sensory innervation in developing teeth

This study shows that Tgfbr2 in dental pulp mesenchyme regulates paracrine signals that guide sensory innervation of developing teeth.