Guangshun Wang

Mechanistic Insights into Human Cathelicidin LL-37-Induced Activation of a Broadly Conserved Bacterial Signaling System

This study shows human antimicrobial peptides like LL-37 activate bacterial PhoQ-PhoP signaling independently of their bactericidal effects, revealing a new mechanism of bacterial response to host peptides.

SAMP: Identifying Antimicrobial Peptides by an Ensemble Learning Model Based on Proportionalized Split Amino Acid Composition

SAMP identifies antimicrobial peptides using an ensemble model with new features, outperforming existing methods on multiple datasets.