Heather A. Simmons

This study infects pregnant rhesus macaques with Spondweni virus and finds placental pathology without fetal harm, contrasting with ZIKV-DAK-induced fetal demise.

This paper describes a reproducible method to generate rhesus macaque induced pluripotent stem cells (RhiPSCs) from MAPT R406W carriers for in vitro modeling of frontotemporal dementia.

This study shows that prenatal Zika virus exposure in macaques disrupts social-emotional development and visual function, independent of viral factors or maternal immunity.

This study infects pregnant rhesus macaques with clade IIb Mpox virus and finds vertical transmission to the fetus and adverse pregnancy outcomes.

This study delivers hIGF1-loaded nanoparticles to the placenta of a pregnant rhesus macaque via uterine artery catheterization, showing successful placental uptake and expression of hIGF1.

This study develops non-viral nanocapsules for in vivo CRISPR-Cas9 delivery to edit neuronal DNA in mice, achieving efficient and safe genome editing in specific neuron types.