Ye Shen

Two sites in the C-terminal β-chain tail mediate interactions of the chaperone clusterin with amyloid beta and other misfolded client proteins

This study identifies two critical sites in the C-terminal β-chain tail of clusterin that mediate its interaction with misfolded proteins, including amyloid β, through experimental and computational approaches.

Retinal glial cells under hypoxia possibly function in mammalian myopia by responding to mechanical stimuli, affecting hormone metabolism and peptide secretion

The paper investigates the role of retinal glial cells under hypoxia in mammalian myopia by analyzing gene expression and pathways related to mechanical stimuli and hormone metabolism.