Author

Ashraya Ravikumar

University of California, San FranciscoORCID 0000-0002-4902-4025Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Christian B. MacdonaldiD· 1 shared Edmond M. LinossiiD· 1 shared Eric Andrew CollissoniD· 1 shared Gabriella O. EstevamiD· 1 shared Harold PimenteliD· 1 shared James S. FraseriD· 1 shared Jingyou RaoiD· 1 shared John A. CapraiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Christian B. MacdonaldORCID

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1 paper

Recent·Most cited

Mapping kinase domain resistance mechanisms for the MET receptor tyrosine kinase via deep mutational scanning

Gabriella O. Estevam, Edmond M. Linossi, Jingyou Rao, Christian B. Macdonald, Ashraya Ravikumar, Karson M Chrispens, John A. Capra, Willow Coyote‐Maestas, Harold Pimentel, Eric Andrew Collisson, Natalia Jura, James S. Fraser

The paper uses deep mutational scanning to analyze MET kinase domain mutations and their resistance to 11 inhibitors, identifying resistance and sensitizing mutations and improving prediction with a protein language model.

eLife · Feb 17, 2025Peer-reviewedCancer Biology