Author
University of California, San FranciscoORCID 0000-0001-8037-9388Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
5 papers
Recent·Most cited
Gilles Rademaker, Grace A. Hernandez, Sumena Dahal…·Rushika M. Perera
This study identifies PCSK9 as a key determinant of metastatic organ preference in pancreatic cancer by regulating cholesterol acquisition and utilization in liver versus lung environments.
Gabriella O. Estevam, Edmond M. Linossi, Jingyou Rao…·James S. Fraser
The paper uses deep mutational scanning to analyze MET kinase domain mutations and their resistance to 11 inhibitors, identifying resistance and sensitizing mutations and improving prediction with a protein language model.
Gabriella O. Estevam, Edmond M. Linossi, Christian B. Macdonald…·James S. Fraser
Audrey M. Hendley, Arjun Arkal Rao, Laura Leonhardt…·Matthias Hebrok
The paper uses single-cell RNA sequencing to analyze murine pancreatic duct cells, identifying heterogeneity and functional roles in disease progression.
Roman E. Reggiardo, Sreelakshmi Velandi Maroli, Haley Halasz…·Daniel H. Kim
This study identifies how mutant KRAS reprograms the noncoding transcriptome, upregulating repetitive noncoding RNAs and inducing IFN-stimulated genes through epigenetic and RNA-based mechanisms.