Small molecule-directed differentiation of submerged-cultured human nasal airway epithelia for respiratory disease modelling
Henriette H. M. Raeven, Georgia N. Ithakisiou, Sacha Spelier, Malina K. Iwanski, Eugene A. Katrukha, Jonne Terstappen, Lisa W. Rodenburg, Aditi Shekhar, Loes A. Oosterhoff, Shannon M.A. Smits, Isabelle S. van der Windt, Lotte T. Azink, Linda H.M. Bijlard, Koen Passier, Sam F.B. van Beuningen, , Gimano D. Amatngalim
This study develops a method to differentiate human nasal epithelial cells into airway-like tissues using small molecules, creating disease models for respiratory conditions.
Cell Reports Medicine · Mar 23, 2026Peer-reviewedCell Biology