Author

Loes A. Oosterhoff

University Medical Center UtrechtORCID 0000-0002-3472-3018Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Assay:CITE-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Cornelis Korstiaan van der EntiD· 2 shared Eric Gerardus HaarmaniD· 2 shared Georgia N. Ithakisiou· 2 shared Gimano D. AmatngalimiD· 2 shared Henriette H. M. RaeveniD· 2 shared Jeffrey Matthijn BeekmaniD· 2 shared Sam F.B. van BeuningeniD· 2 shared Aditi Shekhar· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersCell Biology

Cornelis Korstiaan van der EntORCID

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2 papers

Recent·Most cited

Personalized multi-assay profiling of respiratory motile ciliopathies and mRNA therapy

Georgia N. Ithakisiou, Pim Cleijpool, Henriette H. M. Raeven, Bram M. Bosch, Wessel Hornman, Daniëlle Hoenselaar, Marinos Tziouvelis, Aranka Gerritsen, Matthew B. Smith, Loes A. Oosterhoff, R.B. Bhattacharjee, Zechen Wang, T. Noelle Lombana, Brandon A. Wustman, Cornelis Korstiaan van der Ent, , Bahar Yetkin-Arik

This study develops a personalized multi-assay platform using nasal epithelial cells to assess ciliary function and therapeutic response in primary ciliary dyskinesia.

bioRxiv · May 23, 2026 · PreprintCell Biology

Small molecule-directed differentiation of submerged-cultured human nasal airway epithelia for respiratory disease modelling

Henriette H. M. Raeven, Georgia N. Ithakisiou, Sacha Spelier, Malina K. Iwanski, Eugene A. Katrukha, Jonne Terstappen, Lisa W. Rodenburg, Aditi Shekhar, Loes A. Oosterhoff, Shannon M.A. Smits, Isabelle S. van der Windt, Lotte T. Azink, Linda H.M. Bijlard, Koen Passier, Sam F.B. van Beuningen, , Gimano D. Amatngalim

This study develops a method to differentiate human nasal epithelial cells into airway-like tissues using small molecules, creating disease models for respiratory conditions.

Cell Reports Medicine · Mar 23, 2026Peer-reviewedCell Biology