Synthetic BiologyBMC BiotechnologyPeer-reviewed
A new mRNA structure prediction based approach to identifying improved signal peptides for bone morphogenetic protein 2
Piers Wilkinson, Brian R. Jackson, Hazel L. Fermor, Robert P. Davies
The paper uses mRNA structure prediction to identify improved signal peptides for BMP2, finding that while sequence-based tools show promise, mRNA structure predictions are unreliable for this application.
DOI 10.1186/s12896-024-00858-1