Author

Piers Wilkinson

University of LeedsORCID 0000-0001-9360-1486Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Adam P. Butler· 1 shared Brian R. JacksoniD· 1 shared Charlotte Beaver· 1 shared Elisabeth D. CheniD· 1 shared Emanuel GonçalvesiD· 1 shared Euan A. StronachiD· 1 shared Fiona M. BehaniD· 1 shared Francesco IorioiD· 1 shared

Activity by Year

2018-2024 · peak 1/yr

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10 top collaborators · 29 mutual co-author links

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1 shared paperBioinformatics

Adam P. Butler

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2 papers

Recent·Most cited

Synthetic BiologyBMC BiotechnologyPeer-reviewedMay 23, 2024

A new mRNA structure prediction based approach to identifying improved signal peptides for bone morphogenetic protein 2

Piers Wilkinson, Brian R. Jackson, Hazel L. Fermor, Robert P. Davies

The paper uses mRNA structure prediction to identify improved signal peptides for BMP2, finding that while sequence-based tools show promise, mRNA structure predictions are unreliable for this application.

DOI 10.1186/s12896-024-00858-1

humanbulk RNA-seq

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BioinformaticsBMC GenomicsPeer-reviewedAug 13, 2018

Unsupervised correction of gene-independent cell responses to CRISPR-Cas9 targeting

Francesco Iorio, Fiona M. Behan, Emanuel Gonçalves…·Mathew J. Garnett

CRISPRcleanR reduces false positives in CRISPR-Cas9 screens by correcting gene-independent responses without assuming copy number status.

121 citationstop 2%

humanCRISPR screen

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