Molecular BiologyNature CommunicationsPeer-reviewed
Timed inhibition of CDC7 increases CRISPR-Cas9 mediated templated repair
Beeke Wienert, David N. Nguyen, Alexis Guenther…·Jacob E. Corn
The paper identifies CDC7 inhibition as a method to enhance HDR efficiency in CRISPR-Cas9 gene editing by inducing an early S-phase cell cycle arrest.
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