Author

Francis Wright

University of California, San FranciscoORCID 0000-0002-6471-0648Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Alexander MarsoniD· 1 shared Alexis GuentheriD· 1 shared Beeke WienertiD· 1 shared Bruce R. ConkliniD· 1 shared Chris D. RichardsoniD· 1 shared David N. NguyeniD· 1 shared Georgia L. GregoryiD· 1 shared Jacob E. CorniD· 1 shared

Activity by Year

2020-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Alexander MarsonORCID

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1 paper

Recent·Most cited

Timed inhibition of CDC7 increases CRISPR-Cas9 mediated templated repair

Beeke Wienert, David N. Nguyen, Alexis Guenther, Sharon J. Feng, Melissa N. Locke, Stacia K. Wyman, Jiyung J. Shin, Katelynn R. Kazane, Georgia L. Gregory, Matthew Carter, Francis Wright, Bruce R. Conklin, Alexander Marson, Chris D. Richardson, Jacob E. Corn

The paper identifies CDC7 inhibition as a method to enhance HDR efficiency in CRISPR-Cas9 gene editing by inducing an early S-phase cell cycle arrest.

Nature Communications · Apr 30, 2020Peer-reviewedMolecular Biology