Molecular BiologyPLoS ONEPeer-reviewed
Inflammatory cytokines promote interferon regulatory factor (IRF) transcriptional activity in human pulmonary epithelial cells through the induction of IRF1 by nuclear factor-κB
Amandah Necker‐Brown, Mahmoud Mostafa, Andrei Georgescu…·Robert Charles Newton
This study investigates how inflammatory cytokines like IL-1β and TNF induce IRF1 expression in human pulmonary epithelial cells through NF-κB activation, revealing potential mechanisms in glucocorticoid-resistant diseases.
3 citations