Author
National Heart Centre SingaporeORCID 0000-0002-4921-3555Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
3 papers
Recent·Most cited
Anissa Anindya Widjaja, Wei‐Wen Lim, Sivakumar Viswanathan…·Stuart A. Cook
This study shows that inhibiting IL11 improves healthspan in aged mice by reversing metabolic dysfunction, sarcopenia, and frailty.
Jinrui Dong, Sivakumar Viswanathan, Eleonora Adami…·Anissa Anindya Widjaja
The paper shows that autocrine IL11 signaling in hepatocytes drives lipotoxicity and NASH by causing lipoapoptosis and reactive oxygen species, with protection seen in Il11ra1-deleted mice.
Anissa Anindya Widjaja, Brijesh Kumar Singh, Eleonora Adami…·Stuart A. Cook
This study identifies IL-11 as a key driver of HSC-to-myofibroblast transformation in NASH, showing that targeting IL-11 reduces fibrosis and inflammation in preclinical models.