Author

Noah J. Goff

University of PennsylvaniaORCID 0000-0002-4925-4146Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 2 Research Focus:variant effect prediction· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1

Frequent Co-Authors

Jacob Otto KitzmaniD· 2 shared Kara Anne BernsteiniD· 2 shared Lea M. StaritaiD· 2 shared Matthew W. SnyderiD· 2 shared Shelby L. HemkeriD· 2 shared Silvia CasadeiiD· 2 shared A W XuiD· 1 shared Airi HosokaiiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersGenetics

Jacob Otto KitzmanORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

GeneticsbioRxivPreprintJun 13, 2026

Saturation Genome Editing reveals the functional impact of RAD51D and XRCC2 variants

Silvia Casadei, Matthew W. Snyder, Ivan M. H. Woo…·Lea M. Starita

The paper uses saturation genome editing to assess the functional impact of RAD51D and XRCC2 variants, showing high accuracy in distinguishing pathogenic from benign variants.

DOI 10.64898/2026.06.12.731983

humanwhole-exome sequencing

𝕏 PostBluesky

Cancer BiologybioRxivPreprintJan 11, 2026

High-throughput mapping of 6,888 RAD51D variants identifies distinct biochemical functions needed for homologous recombination and olaparib response

Kristie E. Darrah, Shelby L. Hemker, Yashpal Rawal…·Kara Anne Bernstein

This paper maps 6,888 RAD51D variants to identify biochemical functions critical for homologous recombination and olaparib response, revealing key regions and mechanisms of variant impact.

1 citation

humanDNA methylation

𝕏 PostBluesky