Author

Laurenz De Cock

Ghent University HospitalORCID 0000-0002-4935-6337Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Organism:Drosophila· 1 Approach:experimental assay· 1 Approach:statistical model· 1 Organism:zebrafish· 1

Frequent Co-Authors

Annelies DheedeneiD· 2 shared Boris KereniD· 2 shared Daryl A. ScottiD· 2 shared Eva JacobsiD· 2 shared Lies Vantomme· 2 shared María del Rocío Pérez BacaiD· 2 shared María Palomares‐BraloiD· 2 shared Mathilde NizoniD· 2 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Annelies DheedeneORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Loss-of-function of the Zinc Finger Homeobox 4 (ZFHX4) gene underlies a neurodevelopmental disorder

María del Rocío Pérez Baca, María Palomares‐Bralo, Michiel Vanhooydonck, Lisa Hamerlinck, Eva D’haene, Sebastian Leimbacher, Eva Jacobs, Laurenz De Cock, Erika D’haenens, Annelies Dheedene, Zoë Malfait, Lies Vantomme, Ananilia Silva, Kathleen Rooney, Xiaonan Zhao, , Stephanie Baskin

This study identifies ZFHX4 loss-of-function variants as a cause of a neurodevelopmental disorder with distinctive facial features and brain abnormalities, supported by zebrafish models.

The American Journal of Human Genetics · May 13, 2025Peer-reviewedGenetic & Genomic Medicine

A novel neurodevelopmental syndrome caused by loss-of-function of the Zinc Finger Homeobox 3 (ZFHX3) gene

María del Rocío Pérez Baca, Eva Jacobs, Lies Vantomme, Pontus Leblanc, Elke Bogaert, Annelies Dheedene, Laurenz De Cock, Sadegheh Haghshenas, Aidin Foroutan, Michael A. Levy, Jennifer Kerkhof, Haley McConkey, Chun‐An Chen, Nurit Assia Batzir, Xia Wang, , Dorothea Wand

This paper identifies loss-of-function variants in ZFHX3 as a cause of syndromic intellectual disability and describes its role in chromatin remodeling and DNA methylation.

The American Journal of Human Genetics · Feb 26, 2024Peer-reviewedGenetic & Genomic Medicine