Author

Mike Minh Fernandez

City Of Hope National Medical CenterORCID 0000-0002-4948-8743Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Assay:CRISPR screen· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

Frequent Co-Authors

Kevyn L. HartiD· 1 shared Lei Yu· 1 shared Lili WangiD· 1 shared Qiong JiaiD· 1 shared Ren-Jang LiniD· 1 shared Xuesong WangiD· 1 shared Zhenyu JiaiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

Kevyn L. HartORCID

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1 paper

Recent·Most cited

Engineering oncogenic hotspot mutations on SF3B1 via CRISPR-directed PRECIS mutagenesis

Mike Minh Fernandez, Qiong Jia, Lei Yu, Xuesong Wang, Kevyn L. Hart, Zhenyu Jia, Ren-Jang Lin, Lili Wang

This paper develops PRECIS, a method combining prime editing and a synthetic intron reporter to efficiently generate SF3B1 mutant cell lines that recapitulate cancer-related splicing and CNV events.

Cancer Research Communications · Aug 28, 2024Peer-reviewedCancer Biology