Author

Ren-Jang Lin

Beckman Research InstituteORCID 0000-0002-2738-2438Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Jessica S. KurataiD· 1 shared Kevyn L. HartiD· 1 shared Lei Yu· 1 shared Lili WangiD· 1 shared Mike Minh FernandeziD· 1 shared Qiong JiaiD· 1 shared Xuesong WangiD· 1 shared Zhenyu JiaiD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 21 mutual co-author links

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1 shared paperMolecular Biology

Jessica S. KurataORCID

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2 papers

Recent·Most cited

Cancer BiologyCancer Research CommunicationsPeer-reviewedAug 28, 2024

Engineering oncogenic hotspot mutations on SF3B1 via CRISPR-directed PRECIS mutagenesis

Mike Minh Fernandez, Qiong Jia, Lei Yu…·Lili Wang

This paper develops PRECIS, a method combining prime editing and a synthetic intron reporter to efficiently generate SF3B1 mutant cell lines that recapitulate cancer-related splicing and CNV events.

5 citations

humanCRISPR screen

𝕏 PostBluesky

Molecular BiologybioRxivPreprintJan 30, 2023

Pan-Cancer Biomarker miR-151a Regulates p21 Partially Through p53

Jessica S. Kurata, Ren-Jang Lin

This study identifies miR-151a as a regulator of the cell cycle through p53/p21, showing its dual strands affect p53 differently and linking miR-151a expression to poor survival in tumors.

3 citations

humanstatistical model

𝕏 PostBluesky