Lili Wang

The paper uses long-read sequencing to identify novel lncRNAs generated by SF3B1 mutation and shows they produce functional peptides linked to cancer prognosis.

RNASeek is a generative foundation model for RNA sequence design and functional prediction, using reinforcement learning to optimize RNA properties like stability and cleavage activity.

This paper identifies a U1-U3 snRNA-snoRNA interaction that links SF3B1 mutations to chromatin-state changes and genome instability, with therapeutic potential through antisense oligonucleotides.

The paper assembles the genome of Pavon 76, a Green Revolution wheat cultivar, providing a chromosome-scale reference for CIMMYT-derived wheat and highlighting structural divergence from the standard reference genome.

This paper develops PRECIS, a method combining prime editing and a synthetic intron reporter to efficiently generate SF3B1 mutant cell lines that recapitulate cancer-related splicing and CNV events.