Author

Javier Fernández-Mateos

Universidad de OviedoORCID 0000-0002-4949-4131Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Ahmet AcariD· 1 shared Ahmet Bulent DogruliD· 1 shared Cenk SökmensüeriD· 1 shared Düriye Özer TürkayiD· 1 shared Erdal Birol BostanciiD· 1 shared Gizem Damla YalçıniD· 1 shared Kubra Celikbas YilmaziD· 1 shared Luca BragaiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Ahmet AcarORCID

Mutual co-authors in cluster

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1 paper

Recent·Most cited

Molecular Profiling and High-Content Drug Screening of Metastatic Colorectal Cancer Organoids Reveal Evolutionary Mechanisms of Pan-KRAS Inhibitor Resistance

Gizem Damla Yalçın, Kubra Celikbas Yilmaz, Raffaella Klima, Olcay Kurtulan, Düriye Özer Türkay, Oktay Halit Aktepe, Ahmet Bulent Dogrul, Cenk Sökmensüer, Volkan Öter, Erdal Birol Bostanci, Javier Fernández-Mateos, Suayib Yalcin, Luca Braga, Ahmet Acar

This study uses patient-derived organoids and single-cell RNA sequencing to investigate resistance mechanisms to pan-KRAS inhibitors in metastatic colorectal cancer.

bioRxiv · Jan 14, 2026 · PreprintCancer Biology