Author

Young Jun Shim

Cleveland ClinicORCID 0000-0002-4955-9564Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:mouse· 2 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Keith R. McCraeiD· 2 shared Alessandro S. PinheiroiD· 1 shared Alliefair ScaliseiD· 1 shared Alona A. MerkulovaiD· 1 shared Alvin H. SchmaieriD· 1 shared Ana Acácia S. PinheiroiD· 1 shared Anthony R. SloaniD· 1 shared Anu AggarwaliD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersPathology

Keith R. McCraeORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Bradykinin Contributes to Vasogenic Edema in Murine Experimental Cerebral Malaria

Alessandro S. Pinheiro, Douglas Esteves Teixeira¹, Rodrigo Pacheco Silva-Aguiar, Young Jun Shim, Alona A. Merkulova, Sadiq Silbak, Yelenna Skomorovska-Prokvolit, David Midem, Sidney Ogolla, Bjoern B. Burckhardt, Tanja Gangnus, Júlio Scharfstein, Celso Caruso‐Neves, Owen J. T. McCarty, David Gailani, , Alvin H. Schmaier

This study shows that bradykinin contributes to vasogenic edema in murine cerebral malaria, and its inhibition improves outcomes when combined with artesunate.

Journal of Clinical Investigation · Jul 14, 2026Peer-reviewedPathology

Targeting an Olfactory Receptor Mitigates High Residual Platelet Reactivity and Arterial Thrombosis Through Actin Cytoskeleton Depolymerization

Anu Aggarwal, Vara Prasad VN Josyula, Nancy Wang, Moua Yang, Young Jun Shim, Quinn Patrick Kennedy, Reina Samuel, Naseer Sangwan, Suman Guntupalli, Matthew Godwin, Huijun Edelyn Park, Mariya Ali, Courtney Jennings, Bhairavi Rajasekar, Alliefair Scalise, , Scott J. Cameron

The paper identifies OR2L13 agonists that reduce platelet reactivity and thrombosis by depolymerizing the actin cytoskeleton through HSP27 phosphorylation.

Circulation · Apr 7, 2026Peer-reviewedPhysiology