Author

Reina Samuel

Cleveland Clinic

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Alexis Bernat· 1 shared Alliefair ScaliseiD· 1 shared Anthony R. SloaniD· 1 shared Anu AggarwaliD· 1 shared Bhairavi RajasekariD· 1 shared Courtney JenningsiD· 1 shared Huijun Edelyn ParkiD· 1 shared Jessica Grondolsky· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

Alexis Bernat

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Targeting an Olfactory Receptor Mitigates High Residual Platelet Reactivity and Arterial Thrombosis Through Actin Cytoskeleton Depolymerization

Anu Aggarwal, Vara Prasad VN Josyula, Nancy Wang, Moua Yang, Young Jun Shim, Quinn Patrick Kennedy, Reina Samuel, Naseer Sangwan, Suman Guntupalli, Matthew Godwin, Huijun Edelyn Park, Mariya Ali, Courtney Jennings, Bhairavi Rajasekar, Alliefair Scalise, , Scott J. Cameron

The paper identifies OR2L13 agonists that reduce platelet reactivity and thrombosis by depolymerizing the actin cytoskeleton through HSP27 phosphorylation.

Circulation · Apr 7, 2026Peer-reviewedPhysiology

XPC loss-of-function triggers melanomagenesis through CDKN2A downregulation

Vipin Shankar Chelakkot, Kiara Thomas, Todd Romigh, Alexis Bernat, Reina Samuel, Nihit Goli, Pooja H. Rambhia, Sairekha Ravichandran, Qi‐En Wang, Kevin D. Cooper, Pauline Funchain, Ying Ni, Joshua Arbesman

This study identifies an XPC variant that promotes melanomagenesis by downregulating CDKN2A through promoter binding, independent of its nucleotide excision repair function.

bioRxiv · Apr 3, 2025 · PreprintCancer Biology