Author

Lei Liu

Center for Life SciencesORCID 0000-0002-4966-5914Unclaimed ORCID profile · follow to get notified of new preprints

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Lei Liu12 papers · Huazhong Agricultural University

Biology Disciplines

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Bioinformatics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Research Focus:benchmarking· 1 Approach:contrastive learning· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Bin LiiD· 1 shared Duo Du· 1 shared Fan ZhongiD· 1 shared Guiyu Guan· 1 shared Hao Zhang· 1 shared Haoxiang LiiD· 1 shared Jiqing ZhengiD· 1 shared Shizhang Wan· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 22 mutual co-author links

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1 shared paperMolecular Biology

Bin LiORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintJun 19, 2025

MFPLI: A Computational Framework for Assessing Biological Authenticity of Protein-Ligand Interactions Using Molecular Fingerprints and Structural Features

Hao Zhang, Jiqing Zheng, Haoxiang Li…·Wei He

MFPLI evaluates protein-ligand binding authenticity using deep learning with physicochemical and structural features, achieving high accuracy in distinguishing native conformations from docking poses.

DOI 10.1101/2025.06.19.659858

protein structuredeep learning

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BioinformaticsbioRxivPreprintDec 5, 2023

Enhancing Recognition and Interpretation of Functional Phenotypic Sequences through Fine-Tuning Pre-Trained Genomic Models

Duo Du, Fan Zhong, Lei Liu

This paper fine-tunes pre-trained genomic models on genotype-phenotype datasets to improve DNA sequence classification, achieving high accuracy on the HERV dataset.

1 citation

humanDNA methylation

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