Cancer BiologyMolecular Cancer TherapeuticsPeer-reviewed
Immunomodulation of Pancreatic Cancer via Inhibition of SUMOylation and CD155/TIGIT Pathway
Jorge De la Torre, Utsav Joshi, Himangshu Sonowal…·Rebekah Ruth White
This study shows that combining SUMO E1 inhibition with TIGIT blockade enhances anti-tumor immunity in pancreatic cancer by reducing regulatory T cells and improving T cell reactivity.
5 citations