Author

Chetan Singh Rajpurohit

Baylor College of MedicineORCID 0000-0002-4999-155XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Hui ZhengiD· 3 shared Chuangye Qi· 2 shared Shuo WangiD· 2 shared Anamitra GhoshiD· 1 shared Baijayanti Ghosh· 1 shared Benxia HuiD· 1 shared Chonghui ChengiD· 1 shared Claudio A. SotoiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersNeuroscience

Hui ZhengORCID

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintOct 20, 2026

Astrocytic sEH-EET signaling regulates microglial lysosomal function and suppresses the STING-Type I interferon pathway in Alzheimer's disease

Baijayanti Ghosh, Shuo Wang, Chuangye Qi…·Hui Zheng

This study identifies an astrocyte-microglia signaling axis in Alzheimer's disease where astrocytic sEH limits EET availability, promoting lysosomal clearance of pSTING and suppressing type I IFN signaling.

DOI 10.64898/2026.10.16.759679

mousescRNA-seq

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NeurosciencebioRxivPreprintDec 9, 2025

Astrocyte cell-surface proteomics identified CD44 as an OPN/SPP1 receptor regulating lipid metabolism and glial crosstalk in Alzheimer s disease

Omar Peña-Ramos, Manasee Gedam, Xue Zhang…·Hui Zheng

The paper identifies CD44 as an OPN receptor in astrocytes that regulates lipid metabolism and glial communication in Alzheimer's disease.

2 citations

mouseproteomics

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Molecular BiologybioRxivPreprintMar 22, 2025

Rewired m6A methylation of promoter antisense RNAs in Alzheimer disease regulates global gene transcription in the 3D nucleome

Benxia Hu, Yuqiang Shi, Feng Xiong…·Wenbo Li

The paper identifies AD-associated changes in m6A methylation on promoter antisense RNAs and shows their role in regulating gene expression and neuronal survival in Alzheimer's disease.

DOI 10.1101/2025.03.22.644756

humanbulk RNA-seq

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