Author

Matthew Liu

Children's Hospital of PhiladelphiaORCID 0000-0002-5004-9182Unclaimed ORCID profile · follow to get notified of new preprints

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Matthew Liu2 papers · Stanford University

Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

Gregory G. CajkaiD· 1 shared Nima N. NaseriiD· 1 shared Ophir ShalemiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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3 top collaborators · 3 mutual co-author links

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1 shared paperCell Biology

Gregory G. CajkaORCID

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1 paper

Recent·Most cited

CRISPR associated enzymes are mislocalized to the cytoplasm in iPSC-derived neurons resulting in KRAB-specific degradation

Gregory G. Cajka, Nima N. Naseri, Matthew Liu, Ophir Shalem

This study identifies that dCas9-KRAB mislocalizes to the cytoplasm in iPSC-derived neurons, leading to KRAB-specific degradation, and shows that adding a neuronal-specific NLS restores nuclear localization and expression.

Cell Systems · Sep 1, 2026Peer-reviewedCell Biology