Author

Shivani Chhabra

Icahn School of Medicine at Mount SinaiORCID 0000-0002-5023-3393Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Systems Biology· 2

Signature Assays, Organisms & Methods

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Organism:E. coli· 2 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Robert C. BrewsteriD· 2 shared Vinuselvi ParisuthamiD· 2 shared Md Zulfikar AliiD· 1 shared Sunil GuharajaniD· 1 shared

Activity by Year

2021-2021 · peak 2/yr

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4 top collaborators · 5 mutual co-author links

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2 shared papersSystems Biology

Robert C. BrewsterORCID

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2 papers

Recent·Most cited

Systems BiologybioRxivPreprintNov 16, 2021

Tunable Transcription Factor Library for Robust Quantification of Gene Expression Dynamics in E. coli

Vinuselvi Parisutham, Shivani Chhabra, Md Zulfikar Ali, Robert C. Brewster

The paper introduces a tunable TF library in E. coli to study TF concentration effects on gene regulation, showing distinct roles for ZntR and GalR/GalS.

DOI 10.1101/2021.11.16.468742

E. coliexperimental assay

Systems BiologyCell ReportsPeer-reviewedNov 1, 2021

Quantifying the regulatory role of individual transcription factors in Escherichia coli

Sunil Guharajan, Shivani Chhabra, Vinuselvi Parisutham, Robert C. Brewster

The paper quantifies how individual transcription factors regulate gene expression in E. coli by isolating their effects using synthetic genes and a thermodynamic model.

18 citations

E. coliChIP-seq