Author

Harissios Vliagoftis

University of AlbertaORCID 0000-0002-5029-855XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:metagenomics· 1 Organism:mouse· 1

Frequent Co-Authors

Carmanah D. HunteriD· 1 shared Caylib Durand· 1 shared Charmaine van EedeniD· 1 shared Chelsey BlackmaniD· 1 shared Desiree RedmondiD· 1 shared Elena NetchiporoukiD· 1 shared Gang ZhouiD· 1 shared Jan StorekiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperMolecular Biology

Carmanah D. HunterORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

PAR2 signaling shapes microbial and metabolic remodeling along the gut-lung axis

Ritu Mann‐Nüttel, Riya Jindal, Marie Armbruster, Shivani Mandal, Gang Zhou, Chelsey Blackman, Maryalle Tan, Harissios Vliagoftis, Paul Forsythe

This study investigates how PAR2 signaling influences microbial and metabolic changes across the gut-lung axis in response to HDM exposure, showing compartment-specific effects and sex-dependent differences.

bioRxiv · Sep 12, 2026 · PreprintMicrobiology

A PERK/FOXO1 AXIS LINKS DNA DAMAGE TO FIBROBLAST SURVIVAL IN DIFFUSE CUTANEOUS SYSTEMIC SCLEROSIS

Lamia Khan, Junquin Wang, Carmanah D. Hunter, Charmaine van Eeden, Desiree Redmond, Lisa M. Willis, Caylib Durand, Jan Storek, Kareem Jamani, Udo Douwe J. Mulder, Murray Baron, Janet Elizabeth Pope, Elena Netchiporouk, Jan Willem Cohen Tervaert, Harissios Vliagoftis, , Mohammed S. Osman

This paper identifies a PERK/FOXO1 axis that enables survival of fibroblasts in diffuse cutaneous systemic sclerosis despite DNA damage, and shows that targeting this axis restores apoptosis.

bioRxiv · Feb 18, 2026 · PreprintMolecular Biology