Samuel F. M. Hart

Identification of an Outbreak of Bivalve Transmissible Neoplasia in Soft-Shell Clams (Mya arenaria) in the Puget Sound Using Hemolymph and eDNA Surveys

The paper identifies a new outbreak of transmissible cancer in soft-shell clams in Puget Sound using eDNA surveys and shows the disease originated from a distant location.

A signature-agnostic test for differences between tumor mutation spectra reveals carcinogen and ancestry effects

The paper introduces AMSD, a signature-agnostic metric to detect differences in mutation spectra between groups, showing its effectiveness in identifying carcinogen and ancestry effects.

A telomere-to-telomere map of somatic mutation burden and functional impact in cancer

The paper maps somatic mutation burden and functional impact across the cancer genome using telomere-to-telomere sequencing, revealing novel mutation hotspots and regulatory rewiring mechanisms.

Variation in Natural Infection Outcomes and Cancer Cell Release from Soft-Shell Clams (Mya arenaria) with Bivalve Transmissible Neoplasia

This study tracks BTN progression in soft-shell clams, showing variable outcomes and cancer cell release into seawater above 24% hemolymph cancer levels.

Gene expression in soft-shell clam (Mya arenaria) transmissible cancer reveals survival mechanisms during host infection and seawater transfer