Author

Dorothy Lartey

University of Washington

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1 Ecology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Organism:bacteria (other)· 1 Approach:biophysical modeling· 1 Assay:cryo-EM· 1 Research Focus:development & morphogenesis· 1 Research Focus:ecology & biodiversity· 1 Organism:human· 1

Frequent Co-Authors

Chris E. WilliamsiD· 2 shared Christian SieboldiD· 2 shared Jennifer H. KongiD· 2 shared Lei GaoiD· 2 shared Pragya ParasharaiD· 2 shared Alyssa RiglosiD· 1 shared Angel SantosiD· 1 shared Anna BoyariD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiochemistry

Chris E. WilliamsORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Identification of an Outbreak of Bivalve Transmissible Neoplasia in Soft-Shell Clams (Mya arenaria) in the Puget Sound Using Hemolymph and eDNA Surveys

Sydney A. Weinandt, Zachary J. Child, Dorothy Lartey, Angel Santos, Holden Maxfield, Jordana K. Sevigny, Fiona E. S. Garrett, Peter D. Smith, Rachael M. Giersch, Samuel F. M. Hart, Lucas Rabins, Samuel Kaiser, Anna Boyar, Jan A. Newton, Jesse S. Kerr, , Michael J. Metzger

The paper identifies a new outbreak of transmissible cancer in soft-shell clams in Puget Sound using eDNA surveys and shows the disease originated from a distant location.

Proceedings of the National Academy of Sciences · Jun 23, 2026Peer-reviewedEcology

Design principles of a membrane-spanning ubiquitin ligase

Chris E. Williams, Laura Margaret Nocka, George Hedger, Pragya Parashara, Els Pardon, Naomi R. Latorraca, Ganesh Varma Pusapati, Parijat Sarkar, Dorothy Lartey, Lei Gao, Ljiljana Milenković, Rod Chalk, Jan Steyaert, Susan Marqusee, Loïc Carrique, , Rajat Rohatgi

The paper describes the structure and function of a membrane-spanning E3 ubiquitin ligase complex, revealing its role in developmental processes and linking mutations to human birth defects.

Molecular Cell · May 26, 2026Peer-reviewedBiochemistry

The E3 ubiquitin ligase MGRN1 targets melanocortin receptors MC1R and MC4R via interactions with transmembrane adapters

Pragya Parashara, Lei Gao, Alyssa Riglos, Dorothy Lartey, Sonia B. Sidhu, Tessa Marks, Chris E. Williams, Grace Siauw, Kai-Jing Lee, Anna I. L. Ostrem, Christian Siebold, Michael E. Riffle, Maia Kinnebrew, Teresa M. Gunn, Jennifer H. Kong

This study identifies ATRN and ATRNL1 as transmembrane adapters that recruit MGRN1 to ubiquitinate and degrade MC1R and MC4R, expanding the known substrate repertoire of MGRN1.

Journal of Cell Science · Nov 3, 2025Peer-reviewedCell Biology