Author

Tomáš Otaševič

Masaryk UniversityORCID 0000-0002-5081-9538Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Andrea KnightiD· 1 shared Josef HouseriD· 1 shared Martin PiskáčekiD· 1 shared Martin SmrčkaiD· 1 shared Václav VybíhaliD· 1 shared Vilém JuráňiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperBiochemistry

Andrea KnightORCID

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1 paper

Recent·Most cited

BiochemistryMolecular MedicinePeer-reviewedNov 13, 2024

Undruggable oncoproteins cMyc and NMyc bind to mediator of transcription with superior high affinity

Andrea Knight, Josef Houser, Tomáš Otaševič…·Martin Piskáček

The paper identifies a conserved 9aaTAD region in c-Myc and N-Myc that binds the KIX domain with high affinity, suggesting a potential druggable target for MYC-driven tumors.

3 citations

humanproteomics

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