Josef Houser

This study benchmarks DSF across labs, showing variability in thermal stability parameters due to instruments, workflows, and fluorescence readouts, with harmonization and centralized analysis improving consistency.

This study identifies a novel C-type lectin in Ixodes ricinus ticks, showing its role in blood feeding and potential interactions with host components.

This study investigates how the BRCA1-BARD1 complex interacts with phosphorylated RNAPII CTD through BRCT repeats, revealing its role in RNAPII condensation and transcription-DNA repair coordination.

The paper identifies a conserved 9aaTAD region in c-Myc and N-Myc that binds the KIX domain with high affinity, suggesting a potential druggable target for MYC-driven tumors.