Author

Stephen M. Soisson

Merck & Co., Inc., Rahway, NJ, USA (United States)ORCID 0000-0002-5089-3885Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 1

Frequent Co-Authors

Aasma A. Khan· 1 shared Adam B. Weinglass· 1 shared Alexander S. PowersiD· 1 shared Jennifer M. JohnstoniD· 1 shared Jerry Di Salvo· 1 shared Joseph M. PaggiiD· 1 shared Jun LuiD· 1 shared Naomi R. LatorracaiD· 1 shared

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2024-2024 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Aasma A. Khan

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1 paper

Recent·Most cited

A non-canonical mechanism of GPCR activation

Alexander S. Powers, Aasma A. Khan, Joseph M. Paggi, Naomi R. Latorraca, Sarah Souza, Jerry Di Salvo, Jun Lu, Stephen M. Soisson, Jennifer M. Johnston, Adam B. Weinglass, Ron O. Dror

This study identifies a non-canonical mechanism of GPCR activation where agonists directly rearrange an intracellular loop to regulate signaling, with implications for drug design.

Nature Communications · Nov 16, 2024Peer-reviewedMolecular Biology