Author

Victoria Sanz‐Moreno

Institute of Cancer ResearchORCID 0000-0002-5096-9456Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Adrián Varela-VázqueziD· 1 shared Alexander Carneiro-Figueira· 1 shared Alicia F. C. OkinesiD· 1 shared Amanda Guitián‐CaamañoiD· 1 shared Amelie ZiehmeiD· 1 shared Anxo VidaliD· 1 shared Anya A NicholasiD· 1 shared Athina Stavrodimou· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCancer Biology

Adrián Varela-VázquezORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintAug 27, 2025

LOX inhibition disrupts a collagen-integrin-MYC axis as a translatable targeting strategy in invasive lobular carcinoma

Renée L. Flaherty, Flavia Hughes, George Sflomos…·Cathrin Brisken

LOX inhibition disrupts a collagen-integrin-MYC axis in ILC, halting tumor growth and metastasis with minimal toxicity, offering a new therapeutic strategy.

DOI 10.1101/2025.08.27.672618

humanbulk RNA-seq

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Cancer BiologyNature CommunicationsPeer-reviewedJul 4, 2025

Cx43 Enhances Response to BRAF/MEK Inhibitors by Reducing DNA Repair Capacity

Adrián Varela-Vázquez, Amanda Guitián‐Caamaño, Paula Carpintero-Fernández…·María D. Mayán

This study shows that Cx43 enhances the effectiveness of BRAF/MEKi by reducing DNA repair, leading to increased DNA damage and cellular senescence, and proposes a novel therapeutic approach using sEVs.

11 citations

humanexperimental assay

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