María D. Mayán

Dual Role of Cx43 in Enhancing CDK4/6 Inhibitor Response and Promoting the Elimination of Therapy-Induced Senescent Tumor Cells

This paper identifies Cx43 as a target that enhances CDK4/6 inhibitor efficacy and promotes elimination of therapy-induced senescent tumor cells through senolytic agents.

A novel target associated with senescence and inflammatory signaling in human intervertebral disc degeneration

This study identifies Cx43 as a key regulator of cellular senescence and inflammation in intervertebral disc degeneration, suggesting it as a potential therapeutic target.

Cx43 Enhances Response to BRAF/MEK Inhibitors by Reducing DNA Repair Capacity

This study shows that Cx43 enhances the effectiveness of BRAF/MEKi by reducing DNA repair, leading to increased DNA damage and cellular senescence, and proposes a novel therapeutic approach using sEVs.

Effects of two different compounds on seizure suppression using the zebrafish PTZ-seizure model

This study evaluates two compounds, Tripeptide and CX2, in a zebrafish PTZ-seizure model, finding CX2 more effective in reducing seizures and inflammation.