Patrick T. Hwu

Implementation of ddaE neuron growth mechanism in graph grammar replicates biological features

The paper develops a computational model of ddaE neuron dendrite development using Dynamical Graph Grammar, showing that a single morphogen gradient can generate complex asymmetric branching patterns.

In-vivo dendrite injury drives local mitochondrial contraction and dendrite branching

This study shows that dendrite injury causes mitochondrial contraction and increased dendrite branching, regulated by KCNJ2 and Drp1.

Dendrite injury, but not axon injury, triggers neuroprotection in Drosophila models of neurodegenerative disease.

Weekend light shifts evoke persistent Drosophila circadian neural network desynchrony

This study examines how a 3-hour weekend light shift disrupts circadian rhythms in Drosophila, leading to desynchrony in neural networks and behavioral defects.