Siba R. Das

This paper demonstrates a method to create engineered genetic incompatibilities in Drosophila melanogaster that can be tuned to cause hybrid lethality and are compatible with other engineered strains.

The paper describes a method to produce non-genetically engineered male insects for SIT programs through batch cultivation, achieving high sex-selection rates without genetic modification.

This study simulates a genetic control strategy for Aedes aegypti that combines incompatibility and female-lethality to suppress populations more effectively than gene drives.