NeurosciencebioRxivPreprint
BTK-NLRP3-Caspase1 and Gasdermin D-Caspase 11 pathways jointly drive neuroinflammation and functional impairments in a rat model of psychosocial stress
Soni Tiwari, Zaidan Mohammed, Ekta Yadav…·Simantini Ghosh
This study identifies that both canonical and non-canonical inflammasome pathways drive neuroinflammation and behavioral impairments in a rat model of psychosocial stress, with combined targeting showing greater efficacy.
DOI 10.1101/2025.02.02.636090