Author

Simantini Ghosh

Ashoka UniversityORCID 0000-0002-0791-7255Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Neuroscience· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:mouse· 2 Research Focus:drug response / drug discovery· 1 Organism:rat· 1

Frequent Co-Authors

Itender SinghiD· 2 shared Zaidan MohammediD· 2 shared Amla ChopraiD· 1 shared Aryan TiwariiD· 1 shared Ekta YadaviD· 1 shared John A. OlschowkaiD· 1 shared M. Kerry O’BanioniD· 1 shared Santi Ranjan AttaiD· 1 shared

Activity by Year

2021-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersNeuroscience

Itender SinghORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

BTK-NLRP3-Caspase1 and Gasdermin D-Caspase 11 pathways jointly drive neuroinflammation and functional impairments in a rat model of psychosocial stress

Soni Tiwari, Zaidan Mohammed, Ekta Yadav, Santi Ranjan Atta, Shweta Kaushik, Aryan Tiwari, Amla Chopra, Itender Singh, Simantini Ghosh

This study identifies that both canonical and non-canonical inflammasome pathways drive neuroinflammation and behavioral impairments in a rat model of psychosocial stress, with combined targeting showing greater efficacy.

bioRxiv · Feb 2, 2025 · PreprintNeuroscience

Sustained Interleukin-1β overexpression exacerbates Tau pathology in a murine tauopathy model via cyclooxygenase-1

Simantini Ghosh, Solomon S. Shaftel, Stephanos Kyrkanides, John A. Olschowka, M. Kerry O’Banion

This study shows that sustained IL-1β overexpression worsens tau pathology in mice via COX-1, and COX-1 inhibition reduces phospho-tau and glial activation.

bioRxiv · Feb 10, 2021 · PreprintNeuroscience

Pharmacological Inhibition of BTK reduces neuroinflammation and stress induced anxiety in vivo

Simantini Ghosh, Zaidan Mohammed, Itender Singh

This study shows that BTK inhibition reduces neuroinflammation and anxiety in stressed mice, with stronger effects in females.

bioRxiv · Jan 11, 2021 · PreprintNeuroscience