Author

Karen A. McDonald

University of California, DavisORCID 0000-0002-5145-9968Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

Somen NandiiD· 2 shared Abhaya M. DandekariD· 1 shared Anindya KarmakeriD· 1 shared Anne Huuskonen· 1 shared Anugraha ThyagaturiD· 1 shared Armin OloumiiD· 1 shared Carlito B. LebrillaiD· 1 shared Emrullah KorkmaziD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersBioengineering

Somen NandiORCID

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2 papers

Recent·Most cited

Expression and Characterization of SARS-CoV-2 Spike Protein in Thermothelomyces heterothallica C1

Yakir Ophir, Justin Wong, Katherine R. Haddad, Anne Huuskonen, Anindya Karmaker, Varun Gore, Seongwon Jung, Armin Oloumi, Yiyun Liu, Jingxin Fu, Libo Zhang, Peishan Huang, Shiaki A. Minami, Shruthi Satya Garimella, Anugraha Thyagatur, , Somen Nandi

This study shows that the filamentous fungus Thermothelomyces heterothallica C1 can produce thermostable SARS-CoV-2 spike protein with a human-like glycan profile, comparable to mammalian systems.

Vaccine · Sep 30, 2025Peer-reviewedBioengineering

Plant-based Production and Characterization of a Promising Fc-fusion Protein against Bone Mass Density Loss

Yongao Xiong, Hiroto Hirano, Nancy E. Lane, Somen Nandi, Karen A. McDonald

This study produces and characterizes a plant-based PTH-Fc fusion protein that shows similar potency to PTH (1-34) in binding and activating PTH1R, making it suitable for space medicine applications.

bioRxiv · Jun 5, 2022 · PreprintSynthetic Biology