Carlito B. Lebrilla

This study shows that neonatal EPEC infection disrupts the microbiota-gut-brain axis via NOD1 signaling, leading to long-term neuroimmune and behavioral deficits, and identifies probiotic muropeptides as potential therapeutics.

This study identifies L-fucose as a monosaccharide neuromodulator that enhances synaptic function and mitigates Alzheimer's disease symptoms in mice.

This study shows that the filamentous fungus Thermothelomyces heterothallica C1 can produce thermostable SARS-CoV-2 spike protein with a human-like glycan profile, comparable to mammalian systems.

The paper describes a method to isolate and characterize lipoprotein classes in plasma, revealing unique lipidomic, proteomic, and small RNA signatures for each class.

The paper develops GlycanDIA, a DIA-based workflow for glycan identification and quantification, showing improved sensitivity and the ability to detect low-abundant modified glycans.

The paper introduces GAP-MS to study glycan-dependent PPIs and shows it identifies PPI variations under different glycosylation conditions.

The paper uses human endocervix chips to show that IL-1 receptor antagonists may prevent preterm labor by reducing cervical dysfunction.

The paper shows that N-glycan modifications regulate endothelial-to-hematopoietic transition by affecting glycosylation enzymes and HSPC production.