Author

Franziska Drews

University of WuppertalORCID 0000-0002-5172-6915Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Marcel H. SchulziD· 2 shared Martin C. SimoniD· 2 shared Martin JungiD· 2 shared Sivarajan KarunanithiiD· 2 shared Abdulrahman SalhabiD· 1 shared Angela M. Rodrigues-Viana· 1 shared Gilles GasparoniiD· 1 shared Marcello PirritanoiD· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersGenomics

Marcel H. SchulzORCID

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2 papers

Recent·Most cited

Broad domains of histone marks in the highly compact Paramecium macronuclear genome

Franziska Drews, Abdulrahman Salhab, Sivarajan Karunanithi, Miriam Cheaib, Martin Jung, Marcel H. Schulz, Martin C. Simon

The paper characterizes the epigenomic organization of the Paramecium macronuclear genome, revealing broad histone mark domains and unique transcriptional features.

Genome Research · Apr 1, 2022Peer-reviewedGenomics

Two Piwis with Ago-like functions silence somatic genes at the chromatin level

Franziska Drews, Sivarajan Karunanithi, Ulrike Götz, Simone Marker, Raphaël de Wijn, Marcello Pirritano, Angela M. Rodrigues-Viana, Martin Jung, Gilles Gasparoni, Marcel H. Schulz, Martin C. Simon

The paper investigates the role of two Piwi proteins in transgene-induced silencing in Paramecium, showing they have distinct but overlapping functions in generating and processing siRNAs for chromatin-level gene silencing.

RNA Biology · Oct 18, 2021Peer-reviewedGenetics